Three Exciting New Papers Using Our Platform Technologies

Posted on 05.08.23

One of the best drivers of our product development and commercialization is seeing how customers put our LC-MS products to use. For this reason, we’re always grateful to be included in published research, and in the last few months we’ve seen an influx of them.

Three peer-reviewed papers for emerging MS applications have recently been published by our customer, Regeneron, and our collaborators, the University of Wisconsin and the University of Georgia.

  1. The Journal of Pharmaceutical and Biomedical Analysis published research from the team at Regeneron that included our innovative multinozzle M3 emitter on a MnESI source, to achieve nanospray native MS for studying antibody affinity binding. The article is: “A Generic Platform to Couple Affinity Chromatography with Native Mass Spectrometry for the Analysis of Therapeutic Monoclonal Antibodies.”
  2. Our collaborators at the University of Georgia focused their research on using our MnESI platform for oligo analysis by a new HILIC method. It included our MnESI source and M3 emitters. The paper was published in the Journal for Chromatography A, entitled, “Microflow Liquid Chromatography – Multi – Emitter Nanoelectrospray Mass Spectrometry of Oligonucleotides.”
  3. Proceedings of the National Academy of Sciences (PNAS) has published “High Sensitivity Top-down Proteomics Captures Single Muscle Cell Heterogeneity in Large Proteoforms” by our collaborators at the University of Wisconsin. This work also involved both our MnESI source and M3 emitters.

Congratulations to all three teams on their exciting publications!