MnESI on Native Protein Complexes

The guest speaker Dr. Viner from Thermo Fisher Scientific shared her experience on how to achieve high throughput, sensitivity, and robustness of native protein complex analysis using a Microflow-nanospray ESI-MS (MnESI-MS) platform that seamlessly integrates M3 multinozzle emitter with a Thermo Scientific Orbitrap mass spectrometer.

Learn how the microflow SEC-LC/MS method empowered by the new MnESI platform achieves:

• High data quality similar to the conventional static nanoESI-MS assays, while allows for automated analysis, higher sample throughput, better separation, higher reproducibility and robustness
• Enhanced signal and reduced chemical noise compared to the analytical flow method using a HESI source, which enables sensitive detection of large labile protein complexes.