Microflow Nanospray ESI Source for Thermo Scientific New Generation MS

Microflow-nanospray Electrospray Ionization (MnESI) source that empowers Newomics award-winning M3 multinozzle emitters to multiply your mass spectrometry performance.

Microflow-nanospray Electrospray Ionization (MnESI) source that empowers Newomics award-winning M3 multinozzle emitters to multiply your mass spectrometry performance.

Enhanced Workflow

Built for Thermo Scientific New Generation MS

Sensitivity

5 - 50x

more sensitive compared to conventional methods.

Robustness

CV ≤ 5%

from 300 plasma injections.

Throughput

< 1 min.

per sample. More than 60 samples per hour.

Product Details

Model: IS-T01

Features

  • Empowers Newomics multinozzle emitters for significantly improved LC/MS performance
  • Delivers nanoflow sensitivity and lower detection limit
  • Allows smaller sample amount
  • Enables higher sample throughput and faster analysis speed
  • Achieves high robustness and excellent reproducibility for complex matrix analysis
  • Visualizes spray via high quality imaging system

Specifications

ParameterSpecifications
Ionization Mode

Atmospheric pressure electrospray ionization (ESI), both positive and negative mode.

ESI Probe

Newomics M3 Emitter (refer to M3 Emitter specification)

Open or Closed System

Closed source

Flow Rate

Nano (20 – 1000 nL/min)
Micro (1 – 50 µL/min)

Spray Angle

Fixed angle of 25°

Spray Voltage

0 – 6 kV

Sheath Gas Flow Setting

0 – 30

Auxiliary Gas Flow Setting

0 – 20 (optional)

Translational Stage

Linear XY-axis manual stage, ±5 mm travel distance, 30 µm travel accuracy

Camera

1.3M pixels, 20x ̶ 90x magnification rate, color CMOS sensor, up to 30 fps frame rate

Light Source

Cool white (9000K) 5 mm round LED light, luminous intensity 46400 mcd

Connection

Face seal, finger-tight 10-32 threaded fittings including Thermo nanoViper, IDEX MarvelX and MarvelXACT, Waters ZenFit, Phenomenex SecurityLink, VICI Cheminert C360IZR1, and nanoConnect

Unit Dimension

Width: 25 cm (9.8 in.)
Height: 17.5 cm (6.9 in.)
Depth: 15 cm (5.9 in.)

Unit Weight

3 kg

ModelSpecifications
Catalog # IS-T01

MnESI Source for Thermo Scientific New Generation Mass Spectrometers (e.g. Orbitrap Fusion Lumos, Eclipse, Exploris, and TSQ Altis Triple quadrupole mass spectrometers)

Catalog # IS-T02

MnESI Source for Thermo Scientific Legacy Mass Spectrometers (e.g. Orbitrap Q Exactive mass spectrometers)

Catalog # IS-B01

MnESI Source for Bruker Mass Spectrometers (e.g. maxis II QTOF, timsTOF Pro mass spectrometers)

Performance Highlight

Literature

Events & Training

Bruker User's Meeting

Interfacing Newomics MnESI Platform with Bruker MS for Protein and Peptide Analysis

Na Parra
Senior Director of Marketing, Newomics

Recorded October 23rd, 2020

Watch Video

HUPO Connect 2020 Newomics Poster

Microflow-Nanospary ESI-MS (MnESI-MS) Platform for Human Plasma Proteomics

Authors: Na Parra, Kai Szeto, Pan Mao, Yan Han, and Daojing Wang

Newomics

View Poster

Webinars

Newomics at US HUPO 2021

A New LC-MS Platform for Clinical Proteomics

Na Parra
Senior Director of Marketing, Newomics

Recorded March 10th, 2021

Watch Recorded Webinar

Newomics Native MS Webinar

Newomics MnESI Platform – Multiply Your MS Performance

Na Parra
Senior Director of Marketing, Newomics

Rosa Viner
Program Manager, Thermo Fisher Scientific

Recorded November 19th, 2020

Watch Recorded Webinar