We are excited to share two new peer-reviewed papers for emerging MS applications.
Analytical Chemistry published research from the teams at National Taiwan University, Erasmus University Medical Center, and Oncode Institute, that investigated physiological and phenotypic diversity of tumor cells. They established a highly sensitive platform using nanoflow liquid chromatography (nLC) combined with multinozzle emitter electrospray ionization mass spectrometry for more in-depth single-cell metabolomics profiling.
Read the article from Analytics Chemistry: “Investigating the Metabolic Heterogeneity of Cancer Cells Using Functional Single-Cell Selection and nLC Combined with Multinozzle Emitter Mass Spectrometry”
Our customers at Regeneron developed a parallel reaction monitoring (PRM)-based method for quantifying Fc glycopeptides through combined transitions generated from both glycosidic and peptide bond fragmentation. The paper was published in the Journal of Proteome Research, entitled, “High-Throughput Glycan Profiling of Human Serum IgG Subclasses Using Parallel Reaction Monitoring Peptide Bond Fragmentation of Glycopeptides and Microflow LC-MS.”